Title : NLRP3 Inflammasome Inhibition by MCC950 Reduces Atherosclerotic Lesion Development in Apolipoprotein E-Deficient Mice-Brief Report.

Pub. Date : 2017 Aug

PMID : 28596375






1 Functional Relationships(s)
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1 Bone marrow-derived macrophages and dendritic cells were stimulated with lipopolysaccharide and cholesterol crystals resulting in high levels of interleukin-1beta release, which was inhibited by MCC950. Cholesterol interleukin 1 beta Mus musculus