Pub. Date : 2017 Oct 15
PMID : 28577910
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Over the past decade, a variety of biochemical, spectroscopic, structural and mechanistic studies of IDI-2 have provided mounting evidence that the flavin coenzyme of IDI-2 acts in a most unusual manner - as an acid/base catalyst to mediate a 1,3-proton addition/elimination reaction. | 4,6-dinitro-o-cresol | isopentenyl-diphosphate delta isomerase 2 | Homo sapiens |
| 2 | Over the past decade, a variety of biochemical, spectroscopic, structural and mechanistic studies of IDI-2 have provided mounting evidence that the flavin coenzyme of IDI-2 acts in a most unusual manner - as an acid/base catalyst to mediate a 1,3-proton addition/elimination reaction. | 4,6-dinitro-o-cresol | isopentenyl-diphosphate delta isomerase 2 | Homo sapiens |
| 3 | While not entirely without precedent, IDI-2 is by far the most extensively studied flavoenzyme that employs flavin-mediated acid/base catalysis. | 4,6-dinitro-o-cresol | isopentenyl-diphosphate delta isomerase 2 | Homo sapiens |
| 4 | Thus, IDI-2 serves as an important mechanistic model for understanding this often overlooked, but potentially widespread reactivity of flavin coenzymes. | 4,6-dinitro-o-cresol | isopentenyl-diphosphate delta isomerase 2 | Homo sapiens |