Pub. Date : 1988 Apr
PMID : 2856056
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of serotonin-induced ACTH release in man by clonidine. | Clonidine | proopiomelanocortin | Homo sapiens |
| 2 | The present study investigated the effect of clonidine on fenfluramine-induced ACTH release in six normal volunteers. | Clonidine | proopiomelanocortin | Homo sapiens |
| 3 | The mean plasma ACTH and cortisol levels and the mean maximal changes in these levels were significantly lower during the clonidine + fenfluramine test than during fenfluramine alone. | Clonidine | proopiomelanocortin | Homo sapiens |
| 4 | In conclusion, clonidine blocked the ACTH-releasing activity of fenfluramine in normal humans. | Clonidine | proopiomelanocortin | Homo sapiens |
| 5 | This inhibition of active ACTH release may result from clonidine blockade of fenfluramine-induced activation of central NNA. | Clonidine | proopiomelanocortin | Homo sapiens |
| 6 | Clonidine alone was no more effective than placebo in lowering plasma ACTH and cortisol. | Clonidine | proopiomelanocortin | Homo sapiens |