Title : G protein-coupled receptor 91 signaling in diabetic retinopathy and hypoxic retinal diseases.

Pub. Date : 2017 Oct

PMID : 28539261






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Succinate-mediated GPR91 activation upregulates vascular endothelial growth factor (VEGF) through ERK1/2-C/EBP beta (c-Fos) and/or ERK1/2-COX-2/PGE2 signaling pathways, which in turn, leads to the breakdown of blood-retina barriers in these disorders. Dinoprostone vascular endothelial growth factor A Homo sapiens
2 Succinate-mediated GPR91 activation upregulates vascular endothelial growth factor (VEGF) through ERK1/2-C/EBP beta (c-Fos) and/or ERK1/2-COX-2/PGE2 signaling pathways, which in turn, leads to the breakdown of blood-retina barriers in these disorders. Dinoprostone vascular endothelial growth factor A Homo sapiens