Pub. Date : 1988 Oct
PMID : 2853896
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Propylthiouracil (PTU) was degraded by myeloperoxidase (MPO) or eosinophil peroxidase (EPO), purified from rat bone marrow, in the presence of H2O2 and Cl-. | Propylthiouracil | myeloperoxidase | Rattus norvegicus |
| 2 | Propylthiouracil (PTU) was degraded by myeloperoxidase (MPO) or eosinophil peroxidase (EPO), purified from rat bone marrow, in the presence of H2O2 and Cl-. | Propylthiouracil | myeloperoxidase | Rattus norvegicus |
| 3 | Propylthiouracil (PTU) was degraded by myeloperoxidase (MPO) or eosinophil peroxidase (EPO), purified from rat bone marrow, in the presence of H2O2 and Cl-. | Propylthiouracil | myeloperoxidase | Rattus norvegicus |
| 4 | Propylthiouracil (PTU) was degraded by myeloperoxidase (MPO) or eosinophil peroxidase (EPO), purified from rat bone marrow, in the presence of H2O2 and Cl-. | Propylthiouracil | myeloperoxidase | Rattus norvegicus |
| 5 | The characteristics of PTU degradation by MPO-H2O2-Cl- were similar to those of the chlorinating activity of the peroxidase. | Propylthiouracil | myeloperoxidase | Rattus norvegicus |
| 6 | Hypochlorous acid as well as MPO-H2O2-Cl- also degraded PTU. | Propylthiouracil | myeloperoxidase | Rattus norvegicus |
| 7 | Metabolites of PTU degradation by MPO-H2O2-Cl-, which were separated by C18 reversed phase h.p.l.c., were the same as those produced by hypochlorous acid. | Propylthiouracil | myeloperoxidase | Rattus norvegicus |
| 8 | Of the metabolites of PTU formed by MPO-H2O2-Cl-, one was identified as PTU sulphonic acid (6-propyl-4-hydroxypyrimidine-2-sulphonate) and another seemed to be propyluracil. | Propylthiouracil | myeloperoxidase | Rattus norvegicus |