Title : Connecting Ca2+ and lysosomes to Parkinson disease.

Pub. Date : 2016 Jun 1

PMID : 28529829






1 Functional Relationships(s)
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1 In particular, I highlight defects in lysosomal Ca2+ content and signalling through NAADP-regulated two-pore channels in patient fibroblasts harbouring mutations in the PD-linked genes, GBA1 and LRRK2. NAADP glucosylceramidase beta Homo sapiens