Title : DLX3 interacts with GCM1 and inhibits its transactivation-stimulating activity in a homeodomain-dependent manner in human trophoblast-derived cells.

Pub. Date : 2017 May 17

PMID : 28515447






2 Functional Relationships(s)
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1 The placental transcription factors Distal-less 3 (DLX3) and Glial cell missing-1 (GCM1) have been shown to coordinate the specific regulation of PGF in human trophoblast cell lines. Prostaglandins F distal-less homeobox 3 Homo sapiens
2 Studies revealed that DLX3 binding reduced the transcriptional activity of GCM1, providing a mechanistic explanation of their functional antagonism in regulating PGF promoter activity. Prostaglandins F distal-less homeobox 3 Homo sapiens