Title : Synthesis, characterization and in vitro and in vivo anticancer activity of Pt(iv) derivatives of [Pt(1S,2S-DACH)(5,6-dimethyl-1,10-phenanthroline)].

Pub. Date : 2017 May 30

PMID : 28513693






1 Functional Relationships(s)
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1 The average IC50 values of the platinum(iv) derivatives ranged from 1.26 to 5.39 muM, compared with 1.24 muM for Pt56MeSS, suggesting that the axial ligands have a relatively minor effect on the potency of the compounds. Platinum latexin Homo sapiens