Title : Effects of cardiotonic steroids on isolated perfused kidney and NHE3 activity in renal proximal tubules.

Pub. Date : 2017 Aug

PMID : 28506883






1 Functional Relationships(s)
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1 Our findings indicate the involvement of NKA-SRc-Kinase-Ras-Raf-ERK1/2 pathway in the downregulation of NHE3 by cardiotonic steroids in the renal proximal tubule, promoting a reduction of proximal sodium reabsorption and natriuresis. Sodium solute carrier family 9 member A3 Rattus norvegicus