Pub. Date : 2017 Aug
PMID : 28500234
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Niclosamide, a potent inhibitor of AR variants, significantly enhanced bicalutamide treatment. | Niclosamide | androgen receptor | Homo sapiens |
| 2 | Niclosamide and bicalutamide combination treatment not only suppressed AR and AR variants expression and inhibited their recruitment to the PSA promoter, but also significantly induced apoptosis in bicalutamide- and enzalutamide-resistant CWR22Rv1 and C4-2B MDVR cells. | Niclosamide | androgen receptor | Homo sapiens |
| 3 | Niclosamide and bicalutamide combination treatment not only suppressed AR and AR variants expression and inhibited their recruitment to the PSA promoter, but also significantly induced apoptosis in bicalutamide- and enzalutamide-resistant CWR22Rv1 and C4-2B MDVR cells. | Niclosamide | androgen receptor | Homo sapiens |