Title : The dynamics of early-state transcriptional changes and aggregate formation in a Huntington's disease cell model.

Pub. Date : 2017 May 12

PMID : 28499347






1 Functional Relationships(s)
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1 RESULTS: Rat pheochromocytoma (PC12) cells containing a stably integrated, doxycycline-inducible, eGFP-tagged N-terminal human Htt fragment with an expanded polyQ domain were used to analyse gene expression changes at different stages of mutant Htt aggregation. Doxycycline huntingtin Homo sapiens