Title : Modulation of human neutrophil and monocyte chemotaxis and superoxide responses by recombinant TNF-alpha and GM-CSF.

Pub. Date : 1988 Sep

PMID : 2848761






4 Functional Relationships(s)
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1 Modulation of human neutrophil and monocyte chemotaxis and superoxide responses by recombinant TNF-alpha and GM-CSF. Superoxides tumor necrosis factor Homo sapiens
2 TNF at concentrations higher than 500 units/ml enhanced the generation of superoxide anions by neutrophils stimulated with f-Met-Leu-Phe. Superoxides tumor necrosis factor Homo sapiens
3 GM-CSF was as potent as TNF in enhancing the generation of superoxide response by neutrophils. Superoxides tumor necrosis factor Homo sapiens
4 Inhibition of neutrophil chemotaxis followed by enhancement of the superoxide response by TNF and GM-CSF may provide an attractive mechanism by which these cytokines assist in fighting invading microorganisms. Superoxides tumor necrosis factor Homo sapiens