Title : Critical role of Myc activation in mouse hepatocarcinogenesis induced by the activation of AKT and RAS pathways.

Pub. Date : 2017 Sep 7

PMID : 28481866






1 Functional Relationships(s)
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1 The Tet-On induction of MadMyc in preneoplastic cells significantly inhibited the progression of AKT/HRAS-induced tumours; its induction in transformed cells suppressed their proliferative activity with alterations in lipid metabolism and protein translation. tetramethylenedisulfotetramine thymoma viral proto-oncogene 1 Mus musculus