Pub. Date : 2017 Jun 7
PMID : 28473643
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Glucose-6-phosphate dehydrogenase (G6PD) is the first and rate-limiting enzyme of the pentose phosphate pathway; it catalyzes the conversion of glucose-6-phosphate to 6-phosphogluconate and NADP+ to NADPH and is thought to be the principal source of NADPH for the cytosolic glutathione and thioredoxin antioxidant defense systems. | NADP | 2,4-dienoyl CoA reductase 1, mitochondrial | Mus musculus |
| 2 | Glucose-6-phosphate dehydrogenase (G6PD) is the first and rate-limiting enzyme of the pentose phosphate pathway; it catalyzes the conversion of glucose-6-phosphate to 6-phosphogluconate and NADP+ to NADPH and is thought to be the principal source of NADPH for the cytosolic glutathione and thioredoxin antioxidant defense systems. | NADP | 2,4-dienoyl CoA reductase 1, mitochondrial | Mus musculus |
| 3 | In contrast, G6pd deficiency resulted in increased activities and protein levels of cytosolic isocitrate dehydrogenase 1, an enzyme that catalyzes the conversion of isocitrate to alpha-ketoglutarate and NADP+ to NADPH, in the inner ear. | NADP | 2,4-dienoyl CoA reductase 1, mitochondrial | Mus musculus |