Title : T1R3 homomeric sweet taste receptor regulates adipogenesis through Gαs-mediated microtubules disassembly and Rho activation in 3T3-L1 cells.

Pub. Date : 2017

PMID : 28472098






2 Functional Relationships(s)
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1 Here, we show that stimulation of this receptor with sucralose or saccharin induced disassembly of the microtubules in 3T3-L1 preadipocytes, which was attenuated by overexpression of the dominant-negative mutant of Galphas (Galphas-G226A). Saccharin GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus Mus musculus
2 Here, we show that stimulation of this receptor with sucralose or saccharin induced disassembly of the microtubules in 3T3-L1 preadipocytes, which was attenuated by overexpression of the dominant-negative mutant of Galphas (Galphas-G226A). Saccharin GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus Mus musculus