Title : Platelet-activating factor antagonist BN52021 decreases accumulation of free polyunsaturated fatty acid in mouse brain during ischemia and electroconvulsive shock.

Pub. Date : 1988 Dec

PMID : 2846788






1 Functional Relationships(s)
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1 These data indicate that BN52021 reduces the injury-induced activation of phospholipase A2 and lysophospholipase, which mediate the accumulation of FFA in brain, while having a negligible effect on phospholipase C-mediated degradation of PIP2. Fatty Acids, Nonesterified phospholipase A2, group IB, pancreas Mus musculus