Title : Radiochemistry on electrodes: Synthesis of an 18F-labelled and in vivo stable COX-2 inhibitor.

Pub. Date : 2017

PMID : 28464017






1 Functional Relationships(s)
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1 Current techniques limit radiosynthesis to analogs of the COX-2 inhibitors with fluorine-18 added via a carbon chain, or on an aromatic position which renders the radiolabeled analog less specific towards COX-2, resulting in tracers with low in vivo stability or specificity. Fluorine-18 mitochondrially encoded cytochrome c oxidase II Homo sapiens