Title : Axons regulate Schwann cell expression of the major myelin and NGF receptor genes.

Pub. Date : 1988 Mar

PMID : 2846259






1 Functional Relationships(s)
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1 In this report, we demonstrate that expression of the P0 and MBP genes in rapidly myelinating Schwann cells is sharply reduced upon withdrawal of axons, but that this expression can be substantially restored by agents that raise the intracellular concentration of cyclic AMP. Cyclic AMP myelin basic protein Homo sapiens