Title : Tofacitinib attenuates arthritis manifestations and reduces the pathogenic CD4 T cells in adjuvant arthritis rats.

Pub. Date : 2017 Nov

PMID : 28461107






1 Functional Relationships(s)
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1 Tofacitinib down-regulated significantly the frequency of CD4+IFN-gamma+ T cells and reduced IL-1beta mRNA expression levels in the spleen of the treated rats. tofacitinib Cd4 molecule Rattus norvegicus