Title : Recognition dynamics of dopamine to human Monoamine oxidase B: role of Leu171/Gln206 and conserved water molecules in the active site cavity.

Pub. Date : 2018 May

PMID : 28460566






1 Functional Relationships(s)
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1 Extensive MD simulation studies of dopamine-docked hMAO B structures have revealed the stabilization of amino-terminal of the substrate by a direct and water-mediated interaction of catalytic tyrosines, Gln206, and Leu171 residues. Tyrosine monoamine oxidase B Homo sapiens