Pub. Date : 1988 Oct 25
PMID : 2844815
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A distinct high affinity cAMP isoenzyme immunologically related to brain calmodulin-dependent cGMP phosphodiesterase. | Cyclic AMP | calmodulin 2 | Mus musculus |
| 2 | A cell-specific isozyme of calmodulin (CaM)-dependent phosphodiesterase that exhibits micromolar affinity for cAMP has been purified 900-fold from mouse testis by DEAE chromatography, gel filtration, affinity chromatography with CaM-Sepharose 4B, and isoelectric focusing. | Cyclic AMP | calmodulin 2 | Mus musculus |
| 3 | A cell-specific isozyme of calmodulin (CaM)-dependent phosphodiesterase that exhibits micromolar affinity for cAMP has been purified 900-fold from mouse testis by DEAE chromatography, gel filtration, affinity chromatography with CaM-Sepharose 4B, and isoelectric focusing. | Cyclic AMP | calmodulin 2 | Mus musculus |
| 4 | A cell-specific isozyme of calmodulin (CaM)-dependent phosphodiesterase that exhibits micromolar affinity for cAMP has been purified 900-fold from mouse testis by DEAE chromatography, gel filtration, affinity chromatography with CaM-Sepharose 4B, and isoelectric focusing. | Cyclic AMP | calmodulin 2 | Mus musculus |
| 5 | The highly purified enzyme is stimulated 5-6-fold by CaM in the presence of Ca2+ and hydrolyzes both cAMP and cGMP with anomalous substrate dependence, i.e. high and low affinity components (Km 2 and 20 microM) are observed either in the presence or absence of CaM. | Cyclic AMP | calmodulin 2 | Mus musculus |
| 6 | The highly purified enzyme is stimulated 5-6-fold by CaM in the presence of Ca2+ and hydrolyzes both cAMP and cGMP with anomalous substrate dependence, i.e. high and low affinity components (Km 2 and 20 microM) are observed either in the presence or absence of CaM. | Cyclic AMP | calmodulin 2 | Mus musculus |