Title : Conformational Dynamics and Allostery in E2:E3 Interactions Drive Ubiquitination: gp78 and Ube2g2.

Pub. Date : 2017 May 2

PMID : 28434917






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 G2BR increases the affinity between the RING and Ube2g2 by 50-fold, while the RING catalyzes the transfer of Ub from the Ube2g2~Ub conjugate. g2br ubiquitin conjugating enzyme E2 G2 Homo sapiens
2 G2BR increases the affinity between the RING and Ube2g2 by 50-fold, while the RING catalyzes the transfer of Ub from the Ube2g2~Ub conjugate. g2br ubiquitin conjugating enzyme E2 G2 Homo sapiens
3 In this work, conformational dynamics in Ube2g2 revealed a clear correlation of binding G2BR and RING with the sequential progression toward Ub transfer. g2br ubiquitin conjugating enzyme E2 G2 Homo sapiens