Title : Ionizing radiation induces long-term senescence in endothelial cells through mitochondrial respiratory complex II dysfunction and superoxide generation.

Pub. Date : 2017 Jul

PMID : 28431961






1 Functional Relationships(s)
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1 Then, senescence under these conditions showed persistent activation of p53 pathway and mitochondrial dysfunctions, characterized by O2 - generation, inhibition of respiratory complex II activity and over-expression of SOD2 and GPX1 detoxification enzymes. Superoxides tumor protein p53 Homo sapiens