Title : Vandetanib and ADAM inhibitors synergistically attenuate the pathological migration of EBV-infected retinal pigment epithelial cells by regulating the VEGF-mediated MAPK pathway.

Pub. Date : 2017 Apr

PMID : 28413487






4 Functional Relationships(s)
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1 Vandetanib and ADAM inhibitors synergistically attenuate the pathological migration of EBV-infected retinal pigment epithelial cells by regulating the VEGF-mediated MAPK pathway. vandetanib vascular endothelial growth factor A Homo sapiens
2 Vandetanib is an oral anticancer drug that selectively inhibits the activities of VEGF receptor and epidermal growth factor receptor tyrosine kinase; however, the effects of vandetanib on VEGF in retinal pigment epithelial (RPE) cells have not yet been studied. vandetanib vascular endothelial growth factor A Homo sapiens
3 Vandetanib is an oral anticancer drug that selectively inhibits the activities of VEGF receptor and epidermal growth factor receptor tyrosine kinase; however, the effects of vandetanib on VEGF in retinal pigment epithelial (RPE) cells have not yet been studied. vandetanib vascular endothelial growth factor A Homo sapiens
4 The migratory activity of ARPE19/EBV induced by VEGF was efficiently blocked by vandetanib. vandetanib vascular endothelial growth factor A Homo sapiens