Title : Inhibition by glucocorticoids of PGE2 and ACTH secretion induced by phorbol esters and EGF in rat pituitary cells.

Pub. Date : 1988

PMID : 2838694






1 Functional Relationships(s)
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1 Since in our model, EGF-induced PGE2 secretion is also inhibited by dexamethasone, these results suggest that a lipocortin-like protein could be present in pituitary cells and involved in the effect of TPA and EGF on PGE2, and, at least partly, on ACTH release. Tetradecanoylphorbol Acetate epidermal growth factor Rattus norvegicus