Pub. Date : 2017 Dec 31
PMID : 28385009
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Resveratrol lowered cyclin D1 transcription. | Resveratrol | cyclin D1 | Homo sapiens |
| 2 | Western blot analysis of the effects of resveratrol on upstream cyclin D1 transcriptional signaling, extracellular signal-related kinase (ERK), p90RSK, Akt, and p70S6K revealed inhibition of Akt but not the ERK signaling pathway. | Resveratrol | cyclin D1 | Homo sapiens |
| 3 | Collectively, the results indicate that resveratrol inhibits Huh7-HBx proliferation by decreasing cyclin D1 expression through blockade of Akt signaling. | Resveratrol | cyclin D1 | Homo sapiens |