Pub. Date : 2017 May 24
PMID : 28383086
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The copper transport protein, hCTR1, is proposed to facilitate the cellular uptake of cisplatin, whereas organic cation transport (OCT) is more important for oxaliplatin. | Cisplatin | solute carrier family 31 member 1 | Homo sapiens |
| 2 | It has been reported that both N-terminal and C-terminal metal binding motifs of hCTR1 are highly reactive to cisplatin, which is the initial step of protein assisted cellular uptake of cisplatin. | Cisplatin | solute carrier family 31 member 1 | Homo sapiens |
| 3 | It has been reported that both N-terminal and C-terminal metal binding motifs of hCTR1 are highly reactive to cisplatin, which is the initial step of protein assisted cellular uptake of cisplatin. | Cisplatin | solute carrier family 31 member 1 | Homo sapiens |
| 4 | The different reactivity is consistent with the hypothesis that hCTR1 is more significant in the transport of cisplatin than that of oxaliplatin. | Cisplatin | solute carrier family 31 member 1 | Homo sapiens |