Pub. Date : 2017 Sep
PMID : 28374976
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Peroxisome Proliferator-Activated Receptor alpha Activation Suppresses Cytochrome P450 Induction Potential in Mice Treated with Gemfibrozil. | Gemfibrozil | cytochrome P450, family 21, subfamily a, polypeptide 1 | Mus musculus |
| 2 | In this study, wild-type mice were first fed gemfibrozil-containing diets (0.375%, 0.75% and 1.5%) for 14 days to establish a dose-response relationship for CYP induction. | Gemfibrozil | cytochrome P450, family 21, subfamily a, polypeptide 1 | Mus musculus |
| 3 | So, gemfibrozil induced CYP, and this action was inhibited by activated PPARalpha. | Gemfibrozil | cytochrome P450, family 21, subfamily a, polypeptide 1 | Mus musculus |