Title : d-Fructose-Decorated Poly(ethylene imine) for Human Breast Cancer Cell Targeting.

Pub. Date : 2017 Aug

PMID : 28371343






3 Functional Relationships(s)
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1 The high affinity of GLUT5 transporter for d-fructose in breast cancer cells has been discussed intensely. Fructose solute carrier family 2 member 5 Homo sapiens
2 In this contribution, high molar mass linear poly(ethylene imine) (LPEI) is functionalized with d-fructose moieties to combine the selectivity for the GLUT5 transporter with the delivery potential of PEI for genetic material. Fructose solute carrier family 2 member 5 Homo sapiens
3 Therefore, the introduction of d-fructose shows superior potential for cell targeting, which can be assumed to be GLUT5 dependent. Fructose solute carrier family 2 member 5 Homo sapiens