Pub. Date : 1985 Oct
PMID : 2835961
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | studies showed the presence of doxorubicin (g = 2.0038) and mitozantrone (g = 2.0036) free radicals in human liver microsomes incubated with drug (50 microD) and supplemented with NADPH. | Doxorubicin | 2,4-dienoyl-CoA reductase 1 | Homo sapiens |
| 2 | studies doxorubicin also stimulated a many-fold increase in the rate of microsomal NADPH oxidation and superoxide anion (O2-) production. | Doxorubicin | 2,4-dienoyl-CoA reductase 1 | Homo sapiens |