Title : Resveratrol promotes regression of renal carcinoma cells via a renin-angiotensin system suppression-dependent mechanism.

Pub. Date : 2017 Feb

PMID : 28356937






3 Functional Relationships(s)
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1 The results indicated that resveratrol treatment may suppress growth, induce apoptosis, and decrease AngII, AT1R, VEGF and COX-2 levels in renal carcinoma ACHN and A498 cells. Resveratrol vascular endothelial growth factor A Homo sapiens
2 In addition, resveratrol-induced cell growth suppression and apoptosis were reversed when co-culturing with AT1R or VEGF. Resveratrol vascular endothelial growth factor A Homo sapiens
3 Thus, resveratrol may suppress renal carcinoma cell proliferation and induce apoptosis via an AT1R/VEGF pathway. Resveratrol vascular endothelial growth factor A Homo sapiens