Title : Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation.

Pub. Date : 2017 May 1

PMID : 28356389






1 Functional Relationships(s)
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1 Mechanistically, c-Fos decreases expression and activity of the nuclear receptor LXRalpha, leading to increased hepatic cholesterol and accumulation of toxic oxysterols and bile acids. Oxysterols Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens