Title : A xenograft model reveals that PU.1 functions as a tumor suppressor for multiple myeloma in vivo.

Pub. Date : 2017 May 13

PMID : 28347818






1 Functional Relationships(s)
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1 We introduced the tet-off system into the human myeloma cell lines U266 and KMS12PE that conditionally express PU.1 and demonstrated that PU.1 induces cell cycle arrest and apoptosis in myeloma cells in vitro. tetramethylenedisulfotetramine Spi-1 proto-oncogene Homo sapiens