Title : Hydroxychloroquine sensitizes chronic myeloid leukemia cells to Vγ9Vδ2 T cell-mediated lysis independent of autophagy.

Pub. Date : 2017 May

PMID : 28339029






2 Functional Relationships(s)
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1 We revealed that in a time-dependent manner HCQ induced the expression of NKG2D ligand ULBP4 on the surface of CML cells. Hydroxychloroquine retinoic acid early transcript 1E Homo sapiens
2 In addition, we showed that HCQ did not affect the synthesis or degradation of ULBP4, but induced the translocation of ULBP4 from the cytoplasm to the cell membrane. Hydroxychloroquine retinoic acid early transcript 1E Homo sapiens