Title : Marine Cyclic Guanidine Alkaloids Monanchomycalin B and Urupocidin A Act as Inhibitors of TRPV1, TRPV2 and TRPV3, but not TRPA1 Receptors.

Pub. Date : 2017 Mar 23

PMID : 28333079






1 Functional Relationships(s)
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1 Monanchomycalin B is the most active among all published marine alkaloids (EC50 6.02, 2.84, and 3.25 muM for TRPV1, TRPV2, and TRPV3, correspondingly). Alkaloids latexin Homo sapiens