Title : Evidence that 5-HT stimulates intracellular Ca2+ signalling and activates pannexin-1 currents in type II cells of the rat carotid body.

Pub. Date : 2017 Jul 1

PMID : 28332205






1 Functional Relationships(s)
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1 5-HT also activated an inward current (I5-HT ) in type II cells (EC50 ~200 nm) that was reversibly inhibited by ketanserin (1-10 nm), the Ca2+ chelator BAPTA-AM (5 mum), and low concentrations of carbenoxolone (5 mum), a putative Panx-1 channel blocker. Ketanserin Pannexin 1 Rattus norvegicus