Pub. Date : 1987
PMID : 2832287
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cyproheptadine inhibits the corticotropin releasing hormone (CRH)--induced hormone release in normal subjects. | Cyproheptadine | corticotropin releasing hormone | Homo sapiens |
| 2 | Cyproheptadine inhibits the corticotropin releasing hormone (CRH)--induced hormone release in normal subjects. | Cyproheptadine | corticotropin releasing hormone | Homo sapiens |
| 3 | To further elucidate the inhibitory action of cyproheptadine on ACTH release, we studied the influence of cyproheptadine (0.1 mg/kg body weight) on the corticotropin releasing hormone (CRH)--induced hormone release in normal subjects. | Cyproheptadine | corticotropin releasing hormone | Homo sapiens |
| 4 | To further elucidate the inhibitory action of cyproheptadine on ACTH release, we studied the influence of cyproheptadine (0.1 mg/kg body weight) on the corticotropin releasing hormone (CRH)--induced hormone release in normal subjects. | Cyproheptadine | corticotropin releasing hormone | Homo sapiens |
| 5 | Cyproheptadine led to a significant suppression of the plasma ACTH (p less than 0.05) and serum cortisol (p less than 0.005) response to CRH compared to placebo suggesting a direct inhibitory action of cyproheptadine at the pituitary level. | Cyproheptadine | corticotropin releasing hormone | Homo sapiens |
| 6 | Cyproheptadine led to a significant suppression of the plasma ACTH (p less than 0.05) and serum cortisol (p less than 0.005) response to CRH compared to placebo suggesting a direct inhibitory action of cyproheptadine at the pituitary level. | Cyproheptadine | corticotropin releasing hormone | Homo sapiens |