Title : Identification of an atypical etiological head and neck squamous carcinoma subtype featuring the CpG island methylator phenotype.

Pub. Date : 2017 Mar

PMID : 28314692






1 Functional Relationships(s)
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1 Further distinguishing features of this "CIMP-Atypical" subtype include an antiviral gene expression profile associated with pro-inflammatory M1 macrophages and CD8+ T cell infiltration, CASP8 mutations, and a well-differentiated state corresponding to normal SOX2 copy number and SOX2OT hypermethylation. Cyclic IMP SOX2 overlapping transcript Homo sapiens