Pub. Date : 2017 Mar 16
PMID : 28306503
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, arginine-rich dipeptide repeats (DPRs) derived from C9orf72 hexanucleotide repeat expansions similarly undergo LLPS and induce phase separation of a large set of proteins involved in RNA and stress granule metabolism. | Arginine | C9orf72-SMCR8 complex subunit | Homo sapiens |
| 2 | Together with recent reports showing that DPRs affect nucleocytoplasmic transport, our results point to an important role for arginine-rich DPRs in the pathogenesis of C9orf72 ALS/FTLD. | Arginine | C9orf72-SMCR8 complex subunit | Homo sapiens |