Title : Progressive increase of lysosomal enzyme activities in hippocampus associated with reduction of population spike in a rat model of neurodegeneration.

Pub. Date : 2016 Dec 18

PMID : 28263538






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Specific activity of lysosomal enzyme Cat D was significantly increased in the 3rd week after TMT administration. tmt cathepsin D Rattus norvegicus
2 This reduction of neuronal firing was later accompanied with increase of specific activity of NAGA and Cat D, supporting evidence that lysosomal dysfunction may be one of the primary contributors to TMT-induced neurodegeneration. tmt cathepsin D Rattus norvegicus