Title : Glutathione and thioredoxin systems contribute to recombinant monoclonal antibody interchain disulfide bond reduction during bioprocessing.

Pub. Date : 2017 Jul

PMID : 28262915






1 Functional Relationships(s)
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1 In this work, we show that the glutathione system, in addition to the thioredoxin system, is involved in reducing antibody molecules and the contributions of the two systems can vary depending upon the cell culture process. Glutathione thioredoxin Homo sapiens