Title : NMN Deamidase Delays Wallerian Degeneration and Rescues Axonal Defects Caused by NMNAT2 Deficiency In Vivo.

Pub. Date : 2017 Mar 20

PMID : 28262487






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Axons require the axonal NAD-synthesizing enzyme NMNAT2 to survive. NAD nicotinamide nucleotide adenylyltransferase 2 Mus musculus
2 We have previously proposed that axonal NMNAT2 primarily promotes axon survival by maintaining low levels of its substrate NMN rather than generating NAD; however, this is still debated. NAD nicotinamide nucleotide adenylyltransferase 2 Mus musculus