Pub. Date : 2017 Apr
PMID : 28260069
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | ERCC1 expression in this cell line is high and contributes to its resistance to cisplatin. | Cisplatin | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |
2 | Suppression of ERCC1 decreased XWLC05 proliferation in vitro (IC50 of cisplatin 1.34 microM for shRNA-infected cells vs. 4.54 microM for control cells) and increased the apoptotic rate after treatment with cisplatin (81.2% shRNA cells vs. 58% control cells, P<0.05). | Cisplatin | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |
3 | Suppression of ERCC1 decreased XWLC05 proliferation in vitro (IC50 of cisplatin 1.34 microM for shRNA-infected cells vs. 4.54 microM for control cells) and increased the apoptotic rate after treatment with cisplatin (81.2% shRNA cells vs. 58% control cells, P<0.05). | Cisplatin | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |