Pub. Date : 2017
PMID : 28253265
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | One impediment to the development of CA4 is an inherent conformational instability about the ethylene linker, which joins two aromatic rings. | ethylene | carbonic anhydrase 4 | Homo sapiens |
| 2 | We have previously published preliminary data regarding structurally simplified biphenyl derivatives of CA4, lacking an ethylene linker, which retain anti-proliferative and pro-apoptotic activity, albeit at higher doses. | ethylene | carbonic anhydrase 4 | Homo sapiens |