Title : Species Difference in Sensitivity of Human and Mouse P2X7 Receptors to Inhibitory Effects of Divalent Metal Cations.

Pub. Date : 2017

PMID : 28250280






2 Functional Relationships(s)
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1 It is reported that divalent metal cations (DMCs) inhibit P2X7R activation and that there are species differences in their inhibitory effects. Chlorodimethylsilane purinergic receptor P2X 7 Homo sapiens
2 To extrapolate the findings in experimental animals to humans, these species differences have to be clarified, but species differences in the sensitivity of P2X7R to DMCs between man and mouse have not been demonstrated. Chlorodimethylsilane purinergic receptor P2X 7 Homo sapiens