Pub. Date : 2017
PMID : 28243326
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The research on lapatinib in autophagy, cell cycle arrest and epithelial to mesenchymal transition via Wnt/ErK/PI3K-AKT signaling pathway in human cutaneous squamous cell carcinoma. | Lapatinib | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | In the in vitro experiment, we found that lapatinib interrupted PI3K/AKT/mTOR signaling pathway in human cSCC cells. | Lapatinib | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Furthermore, lapatinib could suppress epithelial to mesenchymal transition (EMT) via Wnt/ErK/PI3K-AKT signaling pathway to represent a promising anticancer drug for cSCC treatment. | Lapatinib | AKT serine/threonine kinase 1 | Homo sapiens |