Title : Knockdown of antiapoptotic genes in breast cancer cells by siRNA loaded into hybrid nanoparticles.

Pub. Date : 2017 Apr 28

PMID : 28230534






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1 In conclusion, silencing antiapoptotic genes such as BCL-2 and BCL-xL through the use of siRNA carried by hybrid nanoparticles showed to be effective in vitro, and presents a promising strategy for pre-clinical analysis, especially when combined with DOX against breast cancer. Doxorubicin BCL2 like 1 Homo sapiens