Pub. Date : 2017 Feb 21
PMID : 28228262
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Combination treatment with the AR signaling inhibitor enzalutamide (ENZ) and the Chk1/2 inhibitor AZD7762 demonstrates synergy with regard to inhibition of AR-CDC6-ATR-Chk1 signaling, ATM phosphorylation induction, and apoptosis in VCaP (mutant p53) and LNCaP-C4-2b (wild-type p53) cells. | enzalutamide | tumor protein p53 | Homo sapiens |
2 | Combination treatment with the AR signaling inhibitor enzalutamide (ENZ) and the Chk1/2 inhibitor AZD7762 demonstrates synergy with regard to inhibition of AR-CDC6-ATR-Chk1 signaling, ATM phosphorylation induction, and apoptosis in VCaP (mutant p53) and LNCaP-C4-2b (wild-type p53) cells. | enzalutamide | tumor protein p53 | Homo sapiens |