Title : Effect of the A-Type Linkage on the Pharmacokinetics and Intestinal Metabolism of Litchi Pericarp Oligomeric Procyanidins.

Pub. Date : 2017 Mar 8

PMID : 28195469






1 Functional Relationships(s)
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1 Rats fed with A-2 and A-3 presented significantly higher levels of shikimic acid and less amount of m(p)-coumaric acid metabolites in vivo and provide insight into the quantitative structure-activity relationship of procyanidin oligomers during metabolism, indicating that procyanidins with A-type linkage could induce an altered metabolic pathway of oligomers in the gastrointestinal system. Shikimic Acid UDP glucuronosyltransferase family 1 member A8 Rattus norvegicus