Title : Smoothened is a poor prognosis factor and a potential therapeutic target in glioma.

Pub. Date : 2017 Feb 14

PMID : 28195165






1 Functional Relationships(s)
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1 Mechanistically, GDC-0449 treatment markedly decreases the expression levels of key Hedgehog pathway component genes (Shh, Patched-1, Patched-2, smoothened, Gli1 and Gli2). HhAntag691 patched 1 Homo sapiens